河北醫(yī)科大學導師：許順江 正文

[導師姓名]
許順江

[所屬院校]
河北醫(yī)科大學

[基本信息]
導師姓名：許順江
性別：男
人氣指數(shù)：579
所屬院校：河北醫(yī)科大學
所屬院系：
職稱：教授
導師類型：
招生專業(yè)：病理學與病理生理學

[通訊方式]
辦公電話：0311 8591 7257
電子郵件：sjxu66@sina.com

[個人簡述]
本人2005年獲河北醫(yī)科大學病理生理學系醫(yī)學博士學位，導師：叢 斌 院士。2005年8月-2008年8月，在澳大利亞新南威爾士大學做博士后。近年來主要從事病理生理學和神經(jīng)科學方面的研究工作。研究領(lǐng)域包括非編碼RNA在神經(jīng)退行性疾病和糖尿病視網(wǎng)膜病變發(fā)病中的作用及分子機制。特別是在老年癡呆研究方面取得重要進展，率先在我省4個城市12個行政區(qū)36個社區(qū)進行了大規(guī)模的流行病學調(diào)查，篩選出老年癡呆的易感人群，并分析了我省老年癡呆發(fā)病的相關(guān)危險因素，通過大量實驗篩選出用于早期識別輕度認知功能障礙的生物標志物，為老年癡呆的早期診斷提供了依據(jù)，同時建立了完善的資料庫和標本庫。在國際知名雜志《Journal of Alzheimer’s Disease》（該雜志5年影響因子4.394，中科院JCR大類二區(qū)）上發(fā)表了4篇系列研究文章?，F(xiàn)在主持國家自然科學基金面上項目1項、河北省國際合作項目1項、河北省自然科學基金項目1項、河北省應用基礎(chǔ)研究計劃重點基礎(chǔ)研究項目1項和省政府資助臨床優(yōu)秀人才培養(yǎng)項目1項以及省衛(wèi)生廳課題多項。作為主研人參與國家自然科學基金課題2項。近五年來以第一作者或通訊作者發(fā)表文章20篇，其中SCI收錄10篇，累計被引用280次。獲得河北醫(yī)學科技獎一等獎2項。申報國家發(fā)明專利三項，已受理待批準。出版專著兩部。兼任河北省實驗動物學會常務理事、河北省醫(yī)學會理事和河北省醫(yī)學會檢驗醫(yī)學分會委員。任《Journal of Alzheimer’s Disease》助理編輯、《Acta Pharmacologica Sinica》和《Invest Ophthalmol Vis Sci》特約審稿人。

[科研工作]
發(fā)表論文情況 以第一或通訊作者發(fā)表文章如下：1. Zhang R, Garrett Q, Zhou H, Wu X, Mao Y, Cui X, Xie B, Liu Z, Cui D, Jiang L, Zhang Q, Xu S. Upregulation of miR-195 accelerates oxidative stress-induced retinal endothelial cell injury by targeting mitofusin 2 in diabetic rats. Mol Cell Endocrinol. 2017 Sep 5452:33-43.2. Xie B, Liu Z, Liu W, Jiang L, Zhang R, Cui D, Zhang Q, Xu S. DNA Methylation and Tag SNPs of the BDNF Gene in Conversion of Amnestic Mild Cognitive Impairment into Alzheimer's Disease: A Cross-Sectional Cohort Study. J Alzheimers Dis. 201758(1):263-274.3. Xie B, Xu Y, Liu Z, Liu W, Jiang L, Zhang R, Cui D, Zhang Q, Xu S. Elevation of Peripheral BDNF Promoter Methylation Predicts Conversion from Amnestic Mild Cognitive Impairment to Alzheimer's Disease: A 5-Year Longitudinal Study. J Alzheimers Dis. 201756(1):391-401. 4. Zhang R, Zhou H, Jiang L, Mao Y, Cui X, Xie B, Cui D, Wang H, Zhang Q, Xu S. MiR-195 dependent roles of mitofusin2 in the mitochondrial dysfunction of hippocampal neurons in SAMP8 mice.Brain Res. 2016 Dec 11652:135-143. 5. Xie B, Liu Z, Jiang L, Liu W, Song M, Zhang Q, Zhang R, Cui D, Wang X, Xu S. Increased Serum miR-206 Level Predicts Conversion from Amnestic Mild Cognitive Impairment to Alzheimer's Disease: A 5-Year Follow-up Study. J Alzheimers Dis. 201755(2):509-520.6. Zhou H, Zhang R, Lu K, Yu W, Xie B, Cui D, Jiang L, Zhang Q, Xu S. Deregulation of miRNA-181c potentially contributes to the pathogenesis of AD by targeting collapsin response mediator protein 2 in mice. J Neurol Sci. 2016 Aug 15367:3-10.7. Xie B, Zhou H, Zhang R, Song M, Yu L, Wang L, Liu Z, Zhang Q, Cui D, Wang X, Xu S. Serum miR-206 and miR-132 as Potential Circulating Biomarkers for Mild Cognitive Impairment. J Alzheimers Dis. 201545(3):721-31. 8. Xu S, Xie B, Song M, Yu L, Wang L, An C, Zhu Q, Han K, Zhao X, Zhang R, Dong L, Chai N, Gao Y, Zhang Q, Wang X. High prevalence of mild cognitive impairment in the elderly: a community-based study in four cities of the Hebei province, china. Neuroepidemiology. 201442(2):123-30. 9. Zhang R, Zhang Q, Niu J, Lu K, Xie B, Cui D, Xu S. Screening of microRNAs associated with Alzheimer's disease using oxidative stress cell model and different strains of senescence accelerated mice. J Neurol Sci. 2014 Mar 15338(1-2):57-64.10. Xu S, Zhang R, Niu J, Cui D, Xie B, Zhang B, Lu K, Yu W, Wang X, Zhang Q. Oxidative stress mediated-alterations of the microRNA expression profile in mouse hippocampal neurons.Int J Mol Sci. 2012 Dec 1113(12):16945-60. 11. Zhang R, Niu J, Cui D, Xie B, Zhang B, Lu K, Yu W, Wang X, Zhang Q, Xu S.Neuroprotective Effects of Pre-Treament with L-Carnitine and Acetyl-L-Carnitine on Ischemic Injury In Vivo and In Vitro. Int. J. Mol. Sci. 2012, 13, 2078-2090.

[教育背景]
以上老師的信息來源于學校網(wǎng)站，如有更新或錯誤，請聯(lián)系我們進行更新或刪除，聯(lián)系方式

河北醫(yī)科大學

本文來源：http://talkofages.com/hebeiyikedaxue/yanjiushengdaoshi_523335.html